Antimicrobial Resistance Market
The global Antimicrobial Resistance market was valued at US$ 9,390.00 Mn in 2020, estimated to reach US$ 13,800.00 Mn in 2030 with a CAGR of 4.68% from 2021-2030
Market Drivers: Impact of Antimicrobial Resistance (AMR) market on healthcare industry
The emergence and spread of drug-resistant pathogens which have acquired new resistance mechanisms, leading to antimicrobial resistance, continues to threaten our ability to treat common infections. Especially alarming is the rapid global spread of multi- and pan-resistant bacteria (also known as “superbugs”) that cause infections that are not treatable with existing antimicrobial medicines such as antibiotics. Antibiotics are becoming increasingly ineffective as drug-resistance spreads globally leading to more difficult to treat infections and death. New antibacterial are urgently needed – for instance, to treat carbapenem-resistant gram-negative bacterial infections as identified in the WHO priority pathogen list. High burden of antibiotic-resistant infections and emergence of multi-drug resistant pathogens have been augmenting the market. These factors have impacted the growth of healthcare industry.
Market Challenges: High medical costs
The cost of health care for patients suffering from resistant infections is higher than care for patients suffering from non-resistant infections due to the extended duration of illness, and increased usage of expensive drugs.
Market Opportunities: Government Funding for controlling the antimicrobial resistance species
The government and various concerned authorities related to AMR market support the funding related to control the AMR species. The various funding related to Businesses, Universities, and Healthcare Partners are as below:
Broad Agency Announcement (BAA): Contracts with educational institutions, nonprofit organizations, state and local government, and private industry for research and development to identify and evaluate strategies to combat antibiotic resistance. Global Healthcare Detection and Response: An international, five-year funding opportunity for partners with experience in healthcare infection detection and response, and/or antibiotic and antifungal resistance across the One Health spectrum. Modeling Infectious Diseases in Healthcare Network (MInD – Healthcare): Established a virtual laboratory where researchers can investigate factors that drive spread of healthcare-associated infections and simulate multiple prevention strategies to estimate their benefits in a timely and cost-effective manner.
Impact of COVID-19 on the Antimicrobial Resistance Market
The COVID-19 crisis has deepened the global understanding of the health and economic implications of an uncontrolled pandemic. It also accentuated the gaps in sustainable funding to address these risks, including investments in R&D of antimicrobial medicines and vaccines, whilst revealing what rapid progress can be made when there is enough political will and enterprise. Opportunities emerging from the COVID-19 pandemic must be seized to bring to the forefront the needs for sustainable investments in R&D of new and effective antibiotics, according to, Director of AMR Global Coordination at WHO. According to WHO, antibiotics present the Achilles heel for universal health coverage and global health security. It needs a global sustained effort including mechanisms for pooled funding and new and additional investments to meet the magnitude of the AMR threat.
Thus, the emergence of COVID-19 has given an opportunity for the antibiotics resistance market towards growth.
Antimicrobial Resistance Market, By Disease
Based on disease type, the market has been categorized into cUTI, cIAI, BSI, CDI, ABSSSI, HABP/VABP, and CABP. cUTI represented the largest segment in the market in 2020 owing to high overall treatment cost and limited treatment alternatives for Gram-negative pathogens, which account for majority of infection cases. Lack of low-cost treatment options for Gram-negative infections limits access to recently approved branded therapies such as Allergan’s Avycaz, Merck’s Zerbaxa, and Melinta Therapeutics’ Vabomere.
Antimicrobial Resistance Market, By Pathogens
Infections due to K. pneumoniae pathogens that are carbapenem-resistant and ESBL-producing held the largest share in 2020. These infections pose treatment challenges for physicians due to high resistance to current treatment substitutes. These infections even though fewer in terms of number of cases in comparison to Gram positive pathogens, they impose a high cost burden as physicians are increasingly shifting towards novel antibiotics such as Allergan’s Avycaz and Melinta Therapeutics’ Vabomere. CDI, conversely, it is anticipated to register the highest CAGR during the forecast period.
Antimicrobial Resistance Market, By Drug Class
Based on drug class, the market has been segmented into oxazolidinones, lipoglycopeptides, tetracyclines, cephalosporins, combination therapies, and others, which includes miscellaneous drug classes. Cephalosporins are leading the market by 21.38% of the overall market revenue in 2020.
Antimicrobial Resistance Market, By End User
By End-User the market is segmented into Hospitals, Clinics, Research Organizations, and other. Hospitals & Clinics form the largest growing segment as the majority of treatment and procedures are carried out in hospitals. Additionally, in 2016, the average consumption of antibiotics for systemic use in hospitals was 2.1 defined daily doses (DDD) per 1,000 people per day. Research Organizations encourage the research & development of new antimicrobial drugs and diagnostics, thus would drive the growth of the market. Global Antibiotic Research & Development Partnership address global public health needs by delivering and developing new or improved antibiotic treatments.
Antimicrobial Resistance Market, By Region
North America was the largest region in terms of revenue in 2020. Numerous drug launches in the market and high treatment cost are supplementing the growth of the regional market.
The U.S. will be a key revenue contributor in the region during the forecast period as guidelines, such as those defined by IDSA for the treatment of CDI, are promoting the use of novel therapies.
Europe was the second largest regional market in the global arena in 2020, supported largely by growing number of antibiotic-resistant infections.
Among the OECD countries, Greece, Italy, and Portugal were ranked as the top 3 consumers of antibiotics in the world, contributing to increased antibiotic resistance in the region.
Recent Developments:
In 2018: A Clostridium difficile infection (CDI) was launched in 2018 by the ACX–362E Pharmaceuticals, an approved antibiotic candidate from the US Food and Drug Administration.
In 2012: The GAIN Act, adopted in 2012 as an expansion of the United States, is now the generation of antibiotic stimuli. Safety and Innovation Act on Food and Drug Administration. The law seeks to encourage the creation of fresh therapies to increase antibiotic resistant diseases and their severity.
Market key Players
Various key players are listed in this report such as Allecra Therapeutics, Procarta Biosystems, Achaogen, Inc., Basilea Pharmaceutica Ltd., MELINTA THERAPEUTICS, INC., Seres Therapeutics, PARATEK therapeutics, Entasis Therapeutics, Tetraphase Pharmaceuticals, Nabriva Therapeutics plc,etc.
Market Taxonomy
By Disease
By Pathogen
By Drug Class
By Region
Key Questions Addressed by the Report
Global Antimicrobial Resistance Market TOC
1 Introduction
1.1 Objective of the Study
1.2 Market definition
1.3 Market Scope
2 Research Methodology
2.1 Data Mining
2.2 Validation
2.3 Primary Interviews
2.4 List of Data Sources
3 Executive Summary
4 Global Antimicrobial Resistance Market Outlook
4.1 Overview
4.2 Market Dynamics
4.2.1 Drivers
4.2.2 Restraints
4.2.3 Opportunities
4.3 Porters Five Force Model
4.4 Value Chain Analysis
5 Global Antimicrobial Resistance Market, By Disease
5.1 Y-o-Y Growth Comparison, By Disease
5.2 Global Antimicrobial Resistance Market Share Analysis, By Disease
5.3 Global Antimicrobial Resistance Market Size and Forecast, By Disease
5.3.1 Acinetobacter baumannii (Carbapenem-Resistant)
5.3.2. Pseudomonas aeruginosa (Carbapenem-Resistant)
5.3.3. Staphylococcus Aureus (Methicillin-Resistant)
5.3.4. E. coli/K. pneumoniae (Carbapenem-Resistant)
5.3.5. Streptococcus pneumoniae (Penicillin-Non-Susceptible)
5.3.6. Clostridium difficile (Cephalosporin-Resistant, Tetracycline-Resistant)
5.3.7. Enterococcus faecium (Vancomycin-Resistant)
5.3.8. Haemophilus Influenzae (Ampicillin-Resistant)
6 Global Antimicrobial Resistance Market, By Pathogen
6.1 Y-o-Y Growth Comparison, By Pathogen
6.2 Global Antimicrobial Resistance Market Share Analysis, By Pathogen
6.3 Global Antimicrobial Resistance Market Size and Forecast, By Pathogen
6.3.1 Acinetobacter baumannii (Carbapenem-Resistant)
6.3.2 Pseudomonas aeruginosa (Carbapenem-Resistant)
6.3.3 Staphylococcus Aureus (Methicillin-Resistant)
6.3.4 E. coli/K. pneumoniae (Carbapenem-Resistant)
6.3.5. Streptococcus pneumoniae (Penicillin-Non-Susceptible)
6.3.6. Clostridium difficile (Cephalosporin-Resistant, Tetracycline-Resistant)
6.3.7. Enterococcus faecium (Vancomycin-Resistant)
6.3.8. Haemophilus Influenzae (Ampicillin-Resistant)
7 Global Antimicrobial Resistance Market, By Drug Class
7.1 Y-o-Y Growth Comparison, By Drug Class
7.2 Global Antimicrobial Resistance Market Share Analysis, By Drug Class
7.3 Global Antimicrobial Resistance Market Size and Forecast, By Drug Class
7.3. 1 Oxazolidinones
7.3.2. Lipoglycopeptides
7.3.3. Tetracyclines
7.3.4. Cephalosporins
7.3.5. Combination
7.3.6 Others
8 Global Antimicrobial Resistance Market, By Region
8.1 Global Antimicrobial Resistance Market Share Analysis, By Region
8.2 Global Antimicrobial Resistance Market Share Analysis, By Region
8.3 Global Antimicrobial Resistance Market Size and Forecast, By Region
9 North America Antimicrobial Resistance Market Analysis and Forecast (2021-2030)
9.1 Introduction
9.2 North America Antimicrobial Resistance Market Share Analysis, By Disease
9.3 North America Antimicrobial Resistance Market Size and Forecast, By Pathogen
9.4 North America Antimicrobial Resistance Market Size and Forecast, By Drug Class
9.5 North America Antimicrobial Resistance Market Size and Forecast, By Country
9.5.1 U.S.
9.5.2 Canada
9.5.3 Mexico
10 Europe Antimicrobial Resistance Market Analysis and Forecast (2021-2030)
10.1 Introduction
10.2 Europe Antimicrobial Resistance Market Share Analysis, By Disease
10.3 Europe Antimicrobial Resistance Market Size and Forecast, By Pathogen
10.4 Europe Antimicrobial Resistance Market Size and Forecast, By Drug Class
10.5 Europe Antimicrobial Resistance Market Size and Forecast, By Country
10.5.1 Germany
10.5.2 France
10.5.3 UK
10.54. Rest of Europe
11 Asia Pacific Antimicrobial Resistance Market Analysis and Forecast (2021-2030)
11.1 Introduction
11.2 Asia Pacific Antimicrobial Resistance Market Share Analysis, By Disease
11.3 Asia Pacific Antimicrobial Resistance Market Size and Forecast, By Pathogen
11.4 Asia Pacific Antimicrobial Resistance Market Size and Forecast, By Drug Class
11.5 Asia Pacific Antimicrobial Resistance Market Size and Forecast, By Country
11.5.1 China
11.5.2 Japan
11.5.3 India
11.5.4. Rest of Asia Pacific
12 Latin America Antimicrobial Resistance Market Analysis and Forecast (2021-2030)
12.1 Introduction
12.2 Latin America Antimicrobial Resistance Market Share Analysis, By Disease
12.3 Latin America Antimicrobial Resistance Market Size and Forecast, By Pathogen
12.4 Latin America Antimicrobial Resistance Market Size and Forecast, By Drug Class
12.5 Latin America Antimicrobial Resistance Market Size and Forecast, Country
12.5.1. Brazil
12.5.2. Rest of Latin America
13 Middle East Antimicrobial Resistance Market Analysis and Forecast (2021-2030)
13.1 Introduction
13.2 Middle East Antimicrobial Resistance Market Share Analysis, By Disease
13.3 Middle East Antimicrobial Resistance Market Size and Forecast, By Pathogen
13.4 Middle East Antimicrobial Resistance Market Size and Forecast, By Drug Class
13.5 Middle East Antimicrobial Resistance Market Size and Forecast, By Country
13.5.1. Saudi Arabia
13.5.2. UAE
13.5.3. Egypt
13.5.4. Kuwait
13.5.5. South Africa
14 Competitive Analysis
14.1 Competition Dashboard
14.2 Market share Analysis of Top Vendors
14.3 Key Development Strategies
15 Company Profiles
15.1 Allecra Therapeutics
15.1.1 Overview
15.1.2 Offerings
15.1.3 Key Financials
15.1.4 Business Segment & Geographic Overview
15.1.5 Key Market Developments
15.1.6 Key Strategies
15.2. Procarta Biosystems
15.2.1 Overview
15.2.2 Offerings
15.2.3 Key Financials
15.2.4 Business Segment & Geographic Overview
15.2.5 Key Market Developments
15.2.6 Key Strategies
15.3. Achaogen. Inc
15.3.1 Overview
15.3.2 Offerings
15.3.3 Key Financials
15.3.4 Business Segment & Geographic Overview
15.3.5 Key Market Developments
15.3.6 Key Strategies
15.4 Basilea Pharmaceutica Ltd
15.4.1 Overview
15.4.2 Offerings
15.4.3 Key Financials
15.4.4 Business Segment & Geographic Overview
15.4.5 Key Market Developments
15.4.6 Key Strategies
15.5 MELINTA THERAPEUTICS, INC
15.5.1 Overview
15.5.2 Offerings
15.5.3 Key Financials
15.5.4 Business Segment & Geographic Overview
15.5.5 Key Market Developments
15.5.6 Key Strategies
15.6 Seres Therapeutics
15.6.1 Overview
15.6.2 Offerings
15.6.3 Key Financials
15.6.4 Business Segment & Geographic Overview
15.6.5 Key Market Developments
15.6.6 Key Strategies
15.7 PARATEK therapeutics
15.7.1 Overview
15.7.2 Offerings
15.7.3 Key Financials
15.7.4 Business Segment & Geographic Overview
15.7.5 Key Market Developments
15.7.6 Key Strategies
15.8 Entasis Therapeutics
15.8.1 Overview
15.8.2 Offerings
15.8.3 Key Financials
15.8.4 Business Segment & Geographic Overview
15.8.5 Key Market Developments
15.8.6 Key Strategies
15.9 Tetraphase Pharmaceuticals
15.9.1 Overview
15.9.2 Offerings
15.9.3 Key Financials
15.9.4 Business Segment & Geographic Overview
15.9.5 Key Market Developments
15.9.6 Key Strategies
15.10 Nabriva Therapeutics plc
15.10.1 Overview
15.10.2 Offerings
15.10.3 Key Financials
15.10.4 Business Segment & Geographic Overview
15.10.5 Key Market Developments
15.10.6 Key Strategies